Vessel manufacturing process

GOOD ENGINEERING PRACTICE (cGEP)
1

When manufacturing the vessel for the pharma/ Biotech industry. what are the cleaning/finish process is expected like passivation/electro polish after fabrication work complete. Is there any routine process need to carry after some years on the vessel.

2

You may want to do an inspection, and based on the inspection some repolishing or repassivation. The inspection is typically just visual, and looking for rust/rouge, or damage.

If something damages the vessel, then you might have to repolish it, and re-passivate it.

Jared

3

Thanks…is pH ( low and high) impacting the vessel life. If yes what is remedial action

4

There are many factors which could cause deterioration of the vessel - you might want to look at vessel liners (disposable technology). You might also consider HDPE plastic vessels. But each of those should undergo preliminary analysis such as extractables/leechables or compatability studies before you invest in new equipment or processes.

Also make sure your current vessels are the correct grade of stainless.

5

thanks JaredCroft for valuable input.