Toc

GOOD VALIDATION PRACTICE (cGVP) CLEANING VALIDATION
1

Dear ,

     1.how to control TOC in DIWater?

     2.What is reason for increase in TOC level?
2

[quote=sridhars]Dear ,

     1.how to control TOC in DIWater?

     2.What is reason for increase in TOC level?[/quote]

It can be controlled by proper validated santization program of DI plant as well distribution loop, Increase of TOC in DI water plant happens due to increase in organic load in ion resins columns. First you can check the organic load in DI column then you can easily rectified this problem.

thanks