Fo value

GOOD VALIDATION PRACTICE (cGVP)
1

Can any one tell me the details for calculating fo value

2

Teh F0 is caluclated by using following formula :

            Fo = ۸ t log10  (Ta-Tb/Z)

۸ t - Cycle time at a particular temperature
Ta - Actual temperature
Tb - Actual cycle temperature (i.e.110 degree) or base temperature
Z = 10.0 Degree centigrade

3

What are the steps for validating the contact plate method for testing microbiological contamination?

4

You can find excellent explanation to F0 value principles at
http://www.fedegari.com/techno.asp#fo

5

You may find useful help at
www.kayeinc.com

thanks
Niraj