Cleaning In Place (CIP) Vs Cleaning Out of Place (COP)

The basic regulatory requirement is to provide pharmaceutical products of highest quality to the patients. A cleaning problem can have various consequences to health, economics, environment and regulatory approvals. Absence of good cleaning, leads to contaminated drugs, which pose risks for patients as well as manufacturing personnel. Regulatory risk includes possible removal of authorization. Economical risk involves production delays and stock shortages or losses but also manifest as public relations problems for a company.

Click here
to read the entire article

This is really very good article and gives a very clear definition idea about the processes. Thank you.