Should i repeat coverage test / riboflavin test for SVP preparation tank each cleaning validation activities ?
Hi,Im doing cv for SVP on the filling machine we take swabs then use TOC for analysis.My questions is this good enough to say my cv has passed.If my results fail must I start using HPLC to quantify what amount of product I have?
Hello
Yes, it’s advisable to repeat the coverage test (riboflavin test) for the Single Use System (SVP) preparation tank during each cleaning validation activity. This ensures the cleaning process effectively removes residues and contaminants, maintaining compliance and product safety. Regular testing helps verify consistency and effectiveness in cleaning procedures.
Thank you 
gregbowers