Water Content determination


can any one explain calculation of sample content for water determination by using the USP method



F is the water equivalency factor of the Reagent, in mg per mL;
C is the used volume, in percent, of the capacity of the buret;
V is the buret volume, in mL; and
KF is the limit or reasonable expected water content in the sample, in percent.

Please give an example.

This is the formula for "how much weight(mg) of the sample to be taken ?

The ultimate reason for this formula is : Take more weight for consistent results. That’s it. Nothing more than that.

you have an instrument with 10 ml burette capacity.

F=6.000 mg/ml(KF Factor )
C= 10% (1 ml of KF Reagent is exptected to cosume for the analysis)[
V=10(Size of the burette)
KF= Limit(specification)= 0.5%

=6 x 10 x 10 / 0.5
= 1200 mg
=1.2 g

This is the way to fix the weight of the sample required for determination of water.

Bujji Kanchi