In addition to water, other chemical solvents are often added to cleaners to boost performance. i.e. 2-Butoxyethanol (butyl), isopropyl alcohol (rubbing alcohol) and d-Limonene. Their main function is to liquefy grease and oils or dissolve solid soil into very small particles so surfactants can more readily perform their function.
In the traditional approach for cleaning in API industries, same solvent is used for cleaning which is used during the synthesis. As the solubility of this solvent is more for that API compare to other solvent. The most widely used cleaning solvent in the industry i.e. methanol, acetone, dimethyl formamide and ethyl acetate.
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