Steam sterilizer validation

Hello I am new here, i have one question regarding uniformity of chamber during sterilization cycle.

What are the limits for Uniformity?


temerature uniformity must be NMT 1.5 degree from the average temperature

Average - min = NMT 1.5 degree C
Maximum - average = NMT 1.5 degree C

Is anyone aware of a vacuum pulse regulatory requirement for autoclaves?