Setting carryover limits

what is the procedure to set the carryover limits if both veterinary and human api are being manufactured in the same facility?

0.2% carry over is generally accepted.

For HPLC
Inject 1000 ppm of Caffeine solution and followed by blank/diluent injection, integrate area of carry over at Caffeine RT in blank injection.
Calc:
Area of Caffeine in blank
%Carry over = ------------------------------------ x 100
Standard area of Caffeine

Generally product carry over is calculated by MACO calculations

And these calculations are three types .1) LD50 (Lethal Dose) 2)Therapeutic daily dose 3) Acceptable daily intake.

More specifically, i am asking about the health based limits & its implementation example while both veterinary & human APIs are manufactured in the same facility.