I’m in the middle of preparing SOP’s/Validation/Qualification for cleaning. One potential issue that has cropped up, is the composition of any detergents used, and how they are a potential contaminant that must be proven removed before production can occur.
This is for a natural health production plant, with the aim of attaining a DEL.
My question is what do people typically use as a cleaning agent? I had read in some supporting documentation that indicated commercial cleansers are not viable because the composition is unknown, and any change in formulation is not readily available. Also, how would one verify that the cleaning agent is not present?
Thanks in advance, any help would be greatly appreciated.