Selected worst product maco value remain same inall group product

Dear All
Pls need help

As described in subject my worst product ios consider as Product A.
now in a group 20 more products are there.

so for all of these 20 product different MACO value derived , or a minimum maco value can be consider.

we are considering minimum value in group.
is it correct?

Dear Nimesh,

i suppose that your worst case was selected based on solubility or hardest to clean criteria, and the selected worst case is not the most potent drug. In this case, it is perfectly acceptable to use the lowest MACO calculated among all the group of analytes, because you are free to set limits more stringent than the calculated MACO. Only be sure to set this procedure in a document (cleaning validation SOP or, better, cleaning validation master plan).

Best regards

Alfred