Method validatioionfor Cleaning Validation

I want to validate a method for cleaning validation of some equipment considering Chloramphenicol as worst product among different Opthalmic products. For this Swab sample is to be collected from the Mixing Tank (Where Swab is previously soaked with Diluent=Mobile phase of the chromatographic condition) and rinse sample is desired to be collected from Cartridge filter which is collected by rinsing the Filter with Water for Injection.

So, when it is needed to validate the method of analysis should I prepare different standard (using different diluent -Mobile phase & WFI) for system suitability and linearity?
Please let me know about this.

Thank you.