Matrix in LVP

I need to solve this debate in matrix of LVP products to choose the worst case, all are in water, freely soluble:
When I have to compare between two different products of multiple components, should I compare the (LD50 IV) absolutely without taking the concentration into account. I mean for example:]
product 1 low LD50 but with low concentration (1% of PRODUCT 1 LD50)
product 2 high LD50 but with high concentration (50% of PRODUCT 2 LD50)
Which of them is the worst case?