How to obtain detection and quantification limits on Agilent HPLC

Hello Everyone!

I would like to know under which criteria you select the noise ranges under system suitability option (Agilent HPLC software). After you select this noise ranges the sytem report a signal /noise relation… useful in stablishing these limits. I did several tests… changing between different noise ranges…some minutes before and after my peak…but every time you changed them it got different ratios…I would like to know how to choose these noise ranges properly…

Thank you!!!:confused: