Forced degradation

GOOD VALIDATION PRACTICE (cGVP) LABORATORY, METHOD AND ANALYTICAL VALIDATION
1

i’m doing analytical method validation for oral solutions for this solutions thermal degradation is required or not?

2

Yes.You have to carry out Thermal degradation studies for Solutions.
Dr.Barve

3

sir,
already i was performed thermal degradation as per our sop and protocol.in that study i was observed,sample volume was decrase and assay was comming above specification lomit.

4

[quote=prince]sir,
already i was performed thermal degradation as per our sop and protocol.in that study i was observed,sample volume was decrase and assay was comming above specification lomit.[/quote]

Please elloborate your question and briefly share your methodology, so that i can comment on it.

thanks