Dose it required?

Dear All
I have one query about validation of Solid oral dosage form.
Dose a sample at blending stage required if lubrication is next


Dear all

I m waiting for the reply pls let me know that analysis is required at blending stage if lubrication is next


Sampling prior to lubrication stage is only required when we optimize the process parameter. We need to collect blend uniformity samples from 10 locations and a pooled sample for physical parameters. Once the process parameters are optimized sampling at this stage is not necessary.