The 30 second equilibration requirement came from EN285 (from Europe, but being adopted world-wide).
The purpose of the requirement is to show that all the air has been removed from the equipment, and that steam has consistent concentration throughout the load.
You have a few options here to meet that requirements. (1) Break the load into smaller parts (so steam can effectively get to every nook/cranny), but then you’ll have to aseptically re-assemble the parts under hood or using sterile connects. (2) Replace some of the tubing to have larger diameter. (3) Shorten some of the lengths of tubing.
Another thing to look at to help see if there is adequate steam penetration is temperature uniformity within the autoclave. There are additional requirements in steam sterilization industry standards that all temperatures are uniform or within +/- of the mean. Have those requirements been met as well? If so, then you have a better argument that the 2 minute equilibration time is adequate. If not, then you still might have air pockets within the chamber.
Overall, I would strongly recommend modifying the load somehow, as your original 10 minutes equilibration time is a quite long, and shows a very tortuous path for steam to have to penetrate to get everywhere.
Also, another thing to consider with tubing assemlies, is that arrangement of the assembly within the sterlizer can have a huge impact on results. A coil of tubing with a low point could cause a puddle to form in the tubing during a run, blocking steam, and therefore causing the sterilization to be innefective. In this case, something might pass validation then when set-up by someone else, there might be less caution to avoid low points, then the load might not get sterilized, and potentially hurt/kill someone due to microbial contamination.
Not to preach. But typically steam sterilization is considered a high risk operation. As the results of incomplete sterilization for some products is serious hurt to the patient.
Regarding the 2 minute equilibration time. Some people have modified the last pre-vac cycle, so that it is less extreme and ramps to the final set-point a little more slowly - if everything else is robust and reliable.