Dead Legs in Water System

Hi all,
my one quation to the discussion about deadlegs, is there in failure event observed in any pharma compny because of <6D deadleg? what is is resion that we want to reduce this to <1.5D?
Pls. share any incident known to the group

you can find here all the informations about usp purified water systems

Long dead legs will have more stagnant water having more microbial growth because water in dead leg doesnot circulate in circulating water,therefore dead legs should be short.According to WHO:TRS 929 (page no 54),dead legs should not be more than 1.5 times of internal diameter(ID) of the pipe,now a days no dead legs pipe lines are installed to solve the water staging problems in water system

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