Cleaning Validation in Formulation

GOOD VALIDATION PRACTICE (cGVP) CLEANING VALIDATION
1

Please clarify me on the MACO.
Is it For one stage or Combined for Total Cleaning Validation.
(Example: MACO is 2000 mg, IS it Calculated per euipiment or sum of all equipment used in formulation)

2

Dear sallunaaz,

you can calculate the MACO per square area.
Then on the basis of this MACO per square area you can validate the cleaning procedure separately for equipment / for each stage / for complete product.

Satish Dange