May I know the specification of grade A Cleanroom for Air Change Rate and HEPA Filter Leak Test?
Thank you
Dear Safni
From ISPE Good pracetice Guide 2008. Air change of Cleanroom grade A (ISO 5) typically range 300 - 600 AC/Hr, but if you used Larminar hood or Isolator this criteria is not concern. You can qualification the air flow velocity in range 0.36-0.45 m/s (PIC/S Guidance value from Annex 1).
HEPA filter installation leak test, you should follow BSEN 1822-4 or ISO 14644-3 that are good refference.
Kiatpornsiri
[COLOR=“sienna”]ISO 7 (Class 10,000)
0.051 - 0.076 m/sec (10 - 15 ft/min) Air Velocity
60 - 90 Airchanges Per hour[/color]
[COLOR=“red”]ISO 5 (Class 100)
0.203 - 0.406 m/sec (40 - 80 ft/min) Air Velocity
240 - 480 Air changes Per hour[/color]